THE BIPHASIC NATURE OF RENAL CALCIFICATION
Open Access
- 1 April 1952
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 95 (4) , 341-346
- https://doi.org/10.1084/jem.95.4.341
Abstract
Renal calcification, induced in rats by an injection of uranium, is accomplished in two stages: a primary accumulation of calcium in association with anions other than phosphate and a secondary conversion of this calcium complex into a precipitate of calcium phosphate. Except for the exclusion of chondroitin sulfate, the nature of the primary anions remains undefined. The accumulation of calcium in the kidney was converted into a precipitate of minimum solubility, and thus the evidence of its primary causation was obliterated. This may well hold true of calcification at other situations.Keywords
This publication has 1 reference indexed in Scilit:
- The colorimetric determination of phosphorusBiochemical Journal, 1932