Abstract
IN 1946 an outbreak of a febrile illness of several days' duration occurred in the borough of Queens, New York City, among residents of a large housing unit. A distinguishing feature of the disease was a maculopapular rash with tiny central vesicles. There were no deaths. The disease was thoroughly investigated by the New York Health Department and the United States Public Health Service with the co-operation of a pest-control operator1 and New York physicians.2 A micro-organism was obtained from the blood of patients, from the tissues of house mice trapped in the building and from mites found in association . . .

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