The Serious Side Effects of the Newer Antiepileptic Drugs: Their Control and Prevention

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Abstract
THIS paper reviews the dangerous as opposed to the relatively benign toxic side effects of Tridione, Paradione, Mesantoin and Phenurone, and proposes a procedure for the administration of these drugs that adequately safeguards both the patient and his doctor. To save space, reviews of dosage, chemistry, mild and regularly reversible side effects, indications for administration and reports of the clinical value of these antiepileptic drugs are omitted.Serious Side EffectsDangerous, often irreversible toxic side effects of these drugs are: for Tridione and Mesantoin, pancytopenia and exfoliative dermatitis; for Tridione, nephrosis; and, for Phenurone, hepatitis. The best studied of these . . .