Ligand‐Independent Degradation of Epidermal Growth Factor Receptor Involves Receptor Ubiquitylation and Hgs, an Adaptor Whose Ubiquitin‐Interacting Motif Targets Ubiquitylation by Nedd4
Open Access
- 16 September 2002
- Vol. 3 (10) , 740-751
- https://doi.org/10.1034/j.1600-0854.2002.31006.x
Abstract
Ligand‐dependent endocytosis of the epidermal growth factor receptor (EGFR) involves recruitment of a ubiquitin ligase, and sorting of ubiquitylated receptors to lysosomal degradation. By studying H...Keywords
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