Fatal Plasmodium falciparum Malaria after an Inadequate Response to Quinine Treatment
- 1 March 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 161 (3) , 577-580
- https://doi.org/10.1093/infdis/161.3.577
Abstract
A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria.This publication has 5 references indexed in Scilit:
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