Monozygotic twins discordant for the Russell‐Silver syndrome

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Abstract
Russell‐Silver syndrome is a disorder of unknown cause. A number of familial cases have suggested autosomal dominant inheritance. We report on monozygotic twins discordant for the Russell‐Silver syndrome. Our findings suggest that the cause of Russell‐Silver syndrome is not explained entirely by genetic factors. The possible role of the intrauterine environment as an etiologic component of Russell‐Silver syndrome is discussed.