A four factor simplex optimization of a serially coupled open tublar columns gas chromatographic system
- 1 May 1996
- journal article
- research article
- Published by Wiley in Journal of High Resolution Chromatography
- Vol. 19 (5) , 277-283
- https://doi.org/10.1002/jhrc.1240190508
Abstract
Optimization of a gas chromatographic system with two capillary columns coupled in series in a single oven for the linear temperature programmed separation of a mixture of C1C10 hydrocarbons has been carried out using the simplex optimization method. The following four selectivity parameters were optimized: the initial temperature of the oven; the initial hold time; the temperature programmed rate; and the pressure at the mid‐point of the system. The optimization procedure was monitored by the Cp criterion.Keywords
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