A new method for synthesizing the antineoplastic nucleosides 1-(2-azido-2-deoxy-.BETA.-D-arabinofuranosyl)cytosine (cytarazid) and 1-(2-amino-2-deoxy-.BETA.-D-arabinofuranosyl)cytosine (cytaramin) from uridine.

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Abstract
A new method was developed for synthesizing of antineoplastic nucleosides 1-(2-azido-2-deoxy-β-D-arabinofuranosyl)cytosine (2) and 1-(2-amino-2-deoxy-β-D-arabinofuranosyl)-cytosine (3) from uridine. The reaction of N3-benzoyluridine derivative (5) with DPPA, triphenylphosphine and diethyl azodicarboxylate gave the desired 2'-azido-arabinosyl derivative (6), which was subsequently transformed to lead 2 and 3.

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