Phenolic cyclisation. Part I. Novel synthesis of 1-substituted isoquinoline and spiro[cycloalkane-1,1′-isoquinoline] derivatives and its application to the total synthesis of isoquinoline alkaloids
- 1 January 1968
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- p. 112-118
- https://doi.org/10.1039/j39680000112
Abstract
Novel syntheses of 1-substituted isoquinoline and spiro[cycloalkane-1,1′-isoquinoline] derivatives were achieved by condensation of 3-hydroxyphenethylamine with carbonyl compounds, and application of this method led to the total synthesis of (±)-coreximine.Keywords
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