Hematopoietic Growth Factors

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Abstract
Experimentalists who study blood and bone marrow have long enjoyed a unique advantage: they can readily obtain those tissues and manipulate them in the laboratory to gain detailed knowledge of hematopoiesis and blood-cell function. In contrast, clinicians who treat pancytopenia in patients whose bone marrow is regenerating after transplantation, suppressed by chemotherapy, or ravaged by primary disease have usually been limited to providing optimal supportive care. Now, from the study of blood and bone marrow, greatly aided by recombinant DNA techniques in academic laboratories and biotechnology firms, has come a new class of potential therapeutic agents—the hematopoietic growth factors. Observations . . .