Tardive Dyskinesia and Skin Pigmentation

Abstract
Within the past 15 years, it has become clear that the continuing administration of neuroleptics can produce several long term side effects, the two most important being tardive dyskinesia (TD) and skin pigmentation. In mental hospital surveys, the proportion of patients with TD has been described as about 30 to 40 per cent. At this point, there is no recognized treatment although some cases improve if the drug is discontinued (Jeste et al, 1979). In addition, TD may increase mortality (Mehta et al, 1978).

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