Streptokinase Resistance Test in a Group of Mediterranean People and its Possible Variations as Regards Sex and Age

Abstract
A streptokinase resistance test (SK-RT) was studied on a group of people from the Mediterranean coast of Spain. Of the studied population, 87.5% required a dose of 250,000 U [units] or less to obtain an adequate neutralization of the circulating antibodies. In none of the cases was the required dose higher than 500,000 U. The average dose was of 132,969 U (SD = 102,269). No significant differences were found between the dose required for men and that required for women. A significantly inferior dose to the average was required for people over 50 years old (.hivin.x = 112,280, SD = 100,459). [The importance of these results for thrombolytic therapy is discussed.].