Drug-Disintegrant Interactions: Binding of Oxymorphone Derivatives

• 1 June 1981
• journal article
• research article
• Published by Elsevier in Journal of Pharmaceutical Sciences
• Vol. 70  (6) , 709-710
• https://doi.org/10.1002/jps.2600700641

Abstract

Keywords

• DRUG-DISINTEGRANT INTERACTIONS—BINDING OF OXYMORPHONE DERIVATIVES TO DISINTEGRATING AGENTS
• DISSOLUTION TESTING
• FREUNDLICH ADSORPTION ISOTHERM
• DISINTEGRATING AGENTS—CARBOXYMETHYLCELLULOSE SODIUM
• SODIUM STARCH GLYCOLATE
• POVIDONE
• AND MODIFIED CORNSTARCH
• BINDING TO OXYMORPHONE DERIVATIVES COMPARED
• OXYMORPHONE DERIVATIVES—BINDING TO DISINTEGRATING AGENTS COMPARED
• FREUNDLICH ADSORPTION ISOTHERM—BINDING OF OXYMORPHONE DERIVATIVES TO DISINTEGRATING AGENTS COMPARED
• ANALGESICS
• NARCOTIC—OXYMORPHONE
• BINDING TO DISINTEGRATING AGENTS COMPARED