Synthesis of 6-Substituted Purine 2′-Azido- and 3′-Azido-Deoxypentopyranoses
- 1 July 1986
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 5 (3) , 331-342
- https://doi.org/10.1080/07328318608069982
Abstract
Various 6-substituted purine 3′-(2′-) azido-3′, 4′-(2′, 4′-) dideoxy-β-DL-erythro-pentopyranoses (1) (2) have been prepared and compared in terms of a substituent electronegativity parameter. The nucleoside 1a (R=NH2) is a good competitive inhibitor of adenosine deaminase.This publication has 15 references indexed in Scilit:
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