TETRAHYDROAMINACRINE IN ANAESTHESIA
Open Access
- 1 July 1965
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 37 (7) , 505-513
- https://doi.org/10.1093/bja/37.7.505
Abstract
Tetrahydroaminacrine was found to produce little more than fleeting improvement of the respiratory depression due to morphine in rabbits. It had no significant effect on the respiratory minute volume in premedicated anaesthetized man. It had a mild cardioinhibitor action in the anaesthetized patient but in those premedicated with atropine, the intensity of the effect was slight, unlike that of neostigmine. Tetrahydroaminacrine was not capable of protecting mice against lethal doses of gallamine triethiodide and was relatively unsatisfactory as an antidote to curarization in man.Keywords
This publication has 1 reference indexed in Scilit:
- TETRAHYDROAMINOACRIDINE: Clinical Use of a Cholinesterase Inhibitor in Conjunction with SuccinylcholineActa Anaesthesiologica Scandinavica, 1962