Radiation-induced Formation of Thymine-thymine Crosslinks
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 46 (3) , 241-246
- https://doi.org/10.1080/09553008414551361
Abstract
The formation of dimers upon γ-irradiation of thymine, thymidine and thymidine-5′-monophosphate in N2O-saturated aqueous solution is reported. A method using capillary gas chromatography-mass spectrometry was developed for their separation and identification. Quantitative measurements reveal that about 50 per cent of OH adduct radicals of thymine undergo dimerization.Keywords
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