Adenovirus Multiplication: Inhibition by Methisazone
- 11 November 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 154 (3750) , 796-797
- https://doi.org/10.1126/science.154.3750.796
Abstract
Methisazone (5 to 40 μM) inhibited the multiplication of types 3, 7, 9, 11, 14, 16, 17, 21, and 28 adenovirus; SV15 (a simian adenovirus) was also inhibited. A study of adenovirus 11 under single-cycle conditions showed that multiplication of the virus was completely inhibited by 30 μM methisazone when addition of the compound was delayed until 13 hours after infection. A survey showed that the structure-activity relations of the action of methisazone against adenoviruses and pox viruses are similar.This publication has 4 references indexed in Scilit:
- TREATMENT OF ECZEMA VACCINATUM WITH N-METHYLISATIN BETA-THIOSEMICARBAZONEThe Lancet, 1966
- CLINICAL EXPERIENCE WITH THE ANTIVIRAL DRUG MARBORAN® (1‐METHYLISATIN 3‐THIOSEMICARBAZONE) *Annals of the New York Academy of Sciences, 1965
- Untersuchungen über Adenovirus-Hämagglutinine der Gruppe I nach RosenArchiv für die gesamte Virusforschung, 1965
- THE STRUCTURE‐ACTIVITY RELATIONSHIPS OF THE ANTIVIRAL CHEMOTHERAPEUTIC ACTIVITY OF ISATIN β‐THIOSEMICARBAZONEBritish Journal of Pharmacology and Chemotherapy, 1960