Synthesis of (–)-steganone
- 1 January 1982
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 2,p. 521-525
- https://doi.org/10.1039/p19820000521
Abstract
A novel, highly efficient route to the key steganone intermediate 2,3,4-trimethoxy-6,7-methylenedioxy-9-(pyrrolidin-1-yl)phenanthrene (8) is described. Resolution of the derived 5,6,7,8-tetrahydro-1,2,3-trimethoxy-10,11-methylenedioxy-8-oxodibenzo[a,c]cyclo-octene-6-carboxylic acid and further elaboration of the relevant enantiomer (11) leads to the first synthesis of enantiomerically pure (–)-steganone (1).This publication has 1 reference indexed in Scilit:
- Total synthesis of (.+-.)-kadsurinJournal of the American Chemical Society, 1977