In a previous report1I discussed some general considerations of the use of tri-ethanolamine. I have found this drug to be of sufficient value to warrant a second report. The tri-ethanolamine used was originally furnished to me by the Carbide and Carbon Chemical Corporation in response to my request for a chemical which would increase the penetration of drugs in their use on the skin. Because of the fact that tri-ethanolamine markedly lowers surface tension, it was at first used solely for this purpose. Combining it with chemicals in certain ointments, however, brought out reactions which have proved to be advantageous therapeutically. Some of these formulas were suggested in my original article and are reported again mainly to reiterate their value. One of the useful properties of tri-ethanolamine has been to facilitate removal of ointments and oily preparations from the skin or hair. I have