Induction of LH Surges by Continuous Infusion of LH-RH

Abstract
Preovulatory LH [luteinizing hormone] surges were measured in cannulated proestrous rats. Such LH peaks were also obtained by infusing pentobarbital-blocked animals with LH-RH [luteinizing hormone-releasing hormone] for periods of up to 20 h; this suggested that the pituitary LH stores were exhausted. The total amount of LH secreted appeared more or less determined by the LH-RH dose, indicating that the size of the releasable LH pool is not fixed.

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