19F NMR imaging of blood oxygenation in the brain
- 1 March 1988
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 6 (3) , 344-352
- https://doi.org/10.1002/mrm.1910060312
Abstract
Perfluorcarbon (PFC) emulsions have been developed as oxygen carrying blood substitutes. High fluorine concentrations allow them to be used in 19F NMR imaging of blood vessels. Furthermore, 19F relaxation times in PFCs are dependent on oxygen tension (pO2) so that NMR imaging may provide a noninvasive method of measuring spatially localized pO2 values in vivo. Using these principles, we have formed 19F images and calculated pO2 maps of the cat brain. © 1988 Academic Press, Inc.This publication has 12 references indexed in Scilit:
- In Vivo 19F NMR Imaging of the Cardiovascular SystemJournal of Computer Assisted Tomography, 1985
- A Spin Echo Chemical Shift MR Imaging TechniqueJournal of Computer Assisted Tomography, 1985
- Interpolative computation of spin‐lattice relaxation times from signal ratiosMagnetic Resonance in Medicine, 1985
- Oxygen Supply of the Blood-Free Perfused Guinea Pig Brain at Three Different TemperaturesPublished by Springer Nature ,1985
- Perfluorinated Organic Liquids and Emulsions as Biocompatible NMR Imaging Agents for 19F and Dissolved OxygenPublished by Springer Nature ,1984
- Quantitative Measurement of Local Cerebral Blood Flow in Humans by Positron Computed Tomography and 15O-WaterJournal of Cerebral Blood Flow & Metabolism, 1983
- Oxygen Transport in Vivo by Means of Perfluorochemical PreparationsNew England Journal of Medicine, 1982
- Protective effect of Fluosol-DA in acute cerebral ischemia.Stroke, 1981
- Fluorocarbons Reduce Myocardial Ischemic Damage After Coronary OcclusionScience, 1981
- Extra‐ and intra‐cranial blood supply to brains of dog and catJournal of Anatomy, 1976