The surface activity of some antihistamines at the air-solution interface
- 1 October 1975
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 27 (10) , 754-758
- https://doi.org/10.1111/j.2042-7158.1975.tb09395.x
Abstract
The surface activity of some antihistamines at the air-solution interface has been examined. Change of the counterion associated with the drug from chloride to maleate or chloro-theophyllinate considerably decreased the critical micelle concentration and increased the surface activity. The effect on surface activity of changes in the nature of the hydrophobic and hydrophilic groups have also been evaluated.Keywords
This publication has 15 references indexed in Scilit:
- Aggregation of antihistamines in aqueous solution. Self-association of some pyridine derivativesThe Journal of Physical Chemistry, 1975
- Micelle formation by some antihistamines in aqueous solutionJournal of Pharmacy and Pharmacology, 1972
- Relationships between Surface Activity and Biological Activity of DrugsJournal of Pharmaceutical Sciences, 1972
- Effect of Chemical Modification on the Surface Activity of Some Phenothiazine DerivativesJournal of Pharmaceutical Sciences, 1970
- Surface chemical and micellar properties of drugs in solutionAdvances in Colloid and Interface Science, 1968
- Light-scattering study of the effect of temperature on the micellar size and shape of a nonionic detergent in aqueous solutionThe Journal of Physical Chemistry, 1968
- Factors Influencing the Surface Activity of Chlorpromazine at the Air-Solution Interface Effect of Inorganic and Organic ElectrolytesJournal of Pharmaceutical Sciences, 1966
- Surface Activity of a Series of Synthetic Non-Ionic DetergentsJournal of Pharmacy and Pharmacology, 1962
- The adsorption of surface active electrolytes at the air/water interfaceTransactions of the Faraday Society, 1954
- The effect of univalent cations on the critical micelle concentration of sodium dodecyl sulphateTransactions of the Faraday Society, 1953