COMPARISON OF SERUM AND LUNG EXTRACTS FOR SURVEYS OF WILD ANIMALS FOR ANTIBODIES TO FRANCISELLA TULARENSIS BIOVAR PALAEARCTICA
- 1 January 1988
- journal article
- research article
- Published by Wildlife Disease Association in Journal of Wildlife Diseases
- Vol. 24 (1) , 10-14
- https://doi.org/10.7589/0090-3558-24.1.10
Abstract
A comparative study of the antibody titer against Francisella tularensis biovar palaearctica in serum and lung extract was made using different immunoassays. Samples were taken from experimentally-infected goshawks (Accipiter gentilis) and European beavers (Castor fiber), and in a field survey of wild beavers. Good accordance between the antibody titer in serum and in lung extract was found in the experimental studies. However, the antibody titer was generally one- to three-fold lower in lung extract than was the titer of serum. Results in the field survey were less reliable. Estimating antibody titer in lung extract is a practical method for surveys for antibody levels, and an alternative to serological surveys, despite lower sensitivity as compared to serum.Keywords
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