FAMILIAL SELECTIVE IgA DEFICIENCY
- 1 January 1972
- journal article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 49 (1) , 71-79
- https://doi.org/10.1542/peds.49.1.71
Abstract
Thirteen subjects with selective IgA deficiency were obtained from five separate families. In three families an autosomal recessive inheritance was apparent while an autosomal dominant inheritance appeared very likely in the two remaining families. An increased incidence of quantitative defects in immunoglobulin synthesis was seen in addition to evidence of abnormal antibody production and increased autoantibody formation.Keywords
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