Microbiological transformations of 3α-acetoxy-17a-aza-D-homo-5α-androstan-17-one and of 3α-acetoxy-5α-androstan-17-one with the fungus Cunninghamella elegans
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 23,p. 2599-2603
- https://doi.org/10.1039/p19770002599
Abstract
3α-Acetoxy-17a-aza-D-homo-5α-androstan-17-one is hydroxylated by Cunninghamella elegans to 3α-acetoxy-6β-hydroxy-, 3α-acetoxy-7α-hydroxy-, 3α,11α-dihydroxy-, and 3α,11β-dihydroxy-17a-aza-D-homo-5α-androstan-17-one, in contrast to the near carbocyclic analogue, 3α-acetoxy-5α-androstan-17-one, which is hydroxylated to 3α-acetoxy-6β,11β-dihydroxy-5α-androstan-17-one, 1β,3α-dihydroxy-5α-androstan-17-one, and 3α-acetoxy-6β-hydroxy-5α-androstane-11,17-dione.This publication has 2 references indexed in Scilit:
- Structure determination of microbiologically hydroxylated Δ4-3-oxosteroids by NMR spectroscopy and its applicationsSteroids, 1964
- Microbiological transformation of steroidsFolia Microbiologica, 1961