Abstract
Ten rats with electrodes aimed at medial forebrain bundle-posterior hypothalamus (MFB), and 4 rats with electrodes aimed at septal area were trained to press for food for 1 hr. per day. Food was available only during this session. After stable weight levels were demonstrated, rewarding brain stimulation was made available during the 1-hr. feeding session. All septal Ss and 4 hypothalamic Ss maintained their weight on this regimen. The other 6 hypothalamic Ss essentially ignored food, spending most of the session self-stimulating, and [image]self-starved.[image] Self-starving Ss had their electrodes extensively in MFB while surviving hypothalamic Ss had their electrodes in more lateral areas.

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