ADENOCARCINOMA OF BARTHOLINS GLAND

  • 1 January 1980
    • journal article
    • research article
    • Vol. 104  (10) , 523-526
Abstract
Bartholin''s gland carcinoma is an uncommon disease representing 0.1% of all female genital malignant neoplasms. Five Bartholin''s gland adenocarcinomas were selected by the criteria of Chamlian and Taylor. Three patients died from metastatic disease within 4 yr; 2 are free of apparent disease 14 mo. and 13 yr, respectively, after initial diagnosis. Poor prognosis was associated with large tumor size, poor histopathologic differentiation and lymph node involvement. Transmission electron microscopy verified the glandular nature of the poorly differentiated lesions. All 5 tumors demonstrated junctional complexes, abundant rough endoplasmic reticulum, secretory vacuoles and glandular formation. Low levels of estrogen receptor and moderate levels of progesterone receptor were present in the 1 case measured. Endogenous peroxidase, and inducible enzyme in estrogen-sensitive tissues, was observed in 2 of the 5 tumors.

This publication has 0 references indexed in Scilit: