The genetic basis for organophosphorus resistance in the Australian sheep blowfly, Lucilia cuprina (Wiedemann) (Diptera, Calliphoridae)

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Abstract
Organophosphate resistance in Lucilia cuprina (Wied.) is shown, by the backcross and discriminating dose technique, to be controlled by two major genetic loci on chromosomes 4 and 6. Respectively designated Rop-1 and Rop-2, they are positioned on the known genetic map. Rop-1 has three resistance alleles and one of these, and the Rop-2 allele, demonstrated stable transmission and expression in the absence of insecticide. Expression of resistance was either intermediate or incompletely dominant depending on locus and stage of maturity. This, and interaction between the loci, suggests that they have different biochemical mechanisms.
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