Alcoholism and gene polymorphisms related to central dopaminergic transmission in the Japanese population
- 1 January 1997
- journal article
- research article
- Published by Wolters Kluwer Health in Psychiatric Genetics
- Vol. 7 (2) , 87-92
- https://doi.org/10.1097/00041444-199722000-00006
Abstract
We examined the association between gene polymorphisms related to central dopaminergic transmission and alcoholism in the Japanese population. Polymorphic gene loci examined included those encoding the dopamine D2 receptor (NcoI site and Ser-Cys site), the dopamine D3 receptor (BalI site), the dopamine D4 receptor (48 bp tandem repeat) and the dopamine transporter (40bp tandem repeat). The genotype distribution at the NcoI site in the dopamine D2 receptor gene differed significantly (p pKeywords
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