Abstract
To evaluate acceptability of and compliance with the Hemoccult-II guaiac test in screening for occult fetal blood, a representative sample of 685 persons 40-74 yr old received slides and invitation without previous notice. Sixty-seven percent accepted. Eight persons (1.7%) had a positive test. Two had rectal cancer, and 2 had adenomas. Acceptability decreased significantly with age in women, but not in men. Eighty-seven percent agreed to repeated screenings with intervals of 1-2 yr. The acceptability was favorable compared with other studies and suggests 70-74 yr as the upper limit for screening. Acceptability may even be increased by further information to the population. Written remainders were effective, but telephone calls were not. Compliance was high, since only 20 persons needed further instructions, and the proportion of false-positive tests suggested that dietary instructions had been followed. The high acceptability favors the planning of a major randomized trial of the possible effect of screening on mortality from colorectal cancer.