Action of dimeric hybrids of native and selectively alkylated ribonuclease A on double-stranded ribonucleic acid
- 1 July 1974
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 141 (1) , 317-320
- https://doi.org/10.1042/bj1410317
Abstract
The hypothesis that both active sites of dimeric ribonuclease A have to be simultaneously available in order to make the enzyme able to degrade double-stranded RNA is tested with purified hybrid dimers of ribonuclease A and its carboxymethylated derivative. The results obtained support the hypothesis.Keywords
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