Immunodepression in hamsters experimentally infected with Opisthorchis viverrini
- 5 June 1987
- journal article
- research article
- Published by Cambridge University Press (CUP) in Journal of Helminthology
- Vol. 61 (2) , 151-156
- https://doi.org/10.1017/s0022149x00009913
Abstract
Hamsters experimentally infected with Opisthorchis viverrini had significant depression of the antibody response to sheep red blood cells. The depression was more severe with prolonged infections. Lymphoproliferative response to phytohaemagglutinin stimulation was also depressed when compared with uninfected controls. The immunodepression in these animals was abolished by anthelmintic treatment, suggesting that the immunodepressive effect is reversible and is associated with active infection.Keywords
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