Philadelphia Chromosome with T(6;22) (P25;q12)

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Abstract
The introduction of chromosome analysis in various blood disorders has proved the high specificity of the Philadelphia chromosome — a G22 member with deleted long arms — in the diagnosis of chronic myelocytic leukemia.1 , 2 More recently, using Giemsa and fluorescence banding technics, Rowley was able to locate the deleted part of chromosome 22 on the long arms of a No. 9 chromosome.3 Since then, the study of large series by other authors has confirmed that the deleted portion translocated to chromosome 9 in the majority of cases of the disorder studied.4 , 5 Translocation on chromosomes 2, 17, 19 and 22 has . . .