EFFECTS OF SUBLINGUAL NITROGLYCERIN ON PULMONARY ARTERIAL PRESSURE IN PATIENTS WITH LEFT VENTRICULAR FAILURE
- 1 January 1959
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 50 (1) , 34-42
- https://doi.org/10.7326/0003-4819-50-1-34
Abstract
Sublingual nitroglycerin administration was demonstrated effective in relief of respiratory and retrosternal distress of paroxysmal nocturnal dyspnea of left heart failure. Using right heart catheterization in hypertensive heart failure patients, nitroglycerin produced significant reduction in the associated pulmonary hypertension in 5 to 15 minutes. Simultaneous changes in brachial arterial pressure, heart rate and cardiac output were minimal. A significant drop was observed in pulmonary wedge pressure and in total pulmonary artery resistance. In one patient angina pectoris resulted in severe pulmonary artery hypertension with prompt relief of pain and hypertension after nitroglycerin. Nitroglycerin has an important place in treatment of paroxysmal dyspnea of left ventricular failure.Keywords
This publication has 2 references indexed in Scilit:
- Chest Pain in Association with Pulmonary Hypertension: Its Similarity to the Pain of Coronary DiseaseCirculation, 1952
- Pulmonary Capillary Pressure in ManJournal of Applied Physiology, 1949