Localisation of factor XIII in human tissues using an immunoperoxidase technique.
Open Access
- 1 May 1984
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 37 (5) , 560-563
- https://doi.org/10.1136/jcp.37.5.560
Abstract
An immunoperoxidase technique has been used to localise clotting factor XIII subunits A and S in human tissues. The presence of factor XIII in placenta and megakaryocytes was confirmed. Factor XIII was also found in fibroblasts, a hitherto unreported finding. Factor XIII subunits were not detected in hepatocytes, although factor XIII was found in fibroblasts in portal tracts. These findings suggest that factor XIII is not synthesised in the liver as previously thought.This publication has 10 references indexed in Scilit:
- An approach to the metabolism of factor XIII.1981
- Plasma Factor XIII Levels in Children with Renal DiseaseNephron, 1981
- β-thromboglobulin levels in the nephrotic syndromeThe American Journal of Medicine, 1980
- Molecular Subunits and Transamidase Activity of Factor XIII During Disseminated Intravascular Coagulation in Acute LeukaemiaThrombosis and Haemostasis, 1980
- Quantitative Estimation of Coagulation Factors in Liver Disease. The Diagnostic and Prognostic Value of Factor XIII, Factor V and PlasminogenThrombosis and Haemostasis, 1978
- Plasma Factor XIII and Platelet Factor XIII in HyperlipaemiaThrombosis and Haemostasis, 1976
- Annotation.British Journal of Haematology, 1975
- Platelet Function in HyperlipoproteinemiaNew England Journal of Medicine, 1974
- Die molekulare Struktur der fibrinstabilisierenden Faktoren des MenschenAnnals of Hematology, 1972