Rationing antibiotic use in neonatal units

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Abstract
In contrast, the organisms responsible for late sepsis have changed. The most commonly isolated organisms from babies with late onset sepsis, responsible for 50% or more episodes of systemic sepsis in Australia,4 the USA,5 Britain6and many other countries, are now coagulase negative staphylococci. Most of these—over 90% of those cultured in Australia—are methicillin resistant.4 Only half of the isolates of coagulase negative staphylococci in Australia are associated with the presence of a central silastic intravascular cannula.4