Renal Functional Reserve in Kidney Donors Assessed in Different Settings Using Scintigraphy
- 1 January 1996
- journal article
- clinical trial
- Published by S. Karger AG in Nephron
- Vol. 73 (2) , 154-157
- https://doi.org/10.1159/000189032
Abstract
Glomerular filtration rate (GFR) was measured in 9 voluntary male kidney donors by scintigraphy. In the basal state, the mean GFR was 96.1 +/- 22 ml/min/1.73 m2. Four weeks after donor nephrectomy, the GFR of the remaining kidney had increased by 22.8 +/- 20.7% (p < 0.05). A protein meal given at this time failed to significantly augment the GFR. The GFR of the grafted kidney increased by 59.7 +/- 24.4% after 6 months (p < 0.01). Renal functional reserve was thus demonstrated in the remaining kidney and the allograft, though a further reserve could not be elicited in the remaining kidney.Keywords
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