BENIGN AND MALIGNANT NEUTROPENIA

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Abstract
Even now, thirty-two years after the first recorded observations on neutropenia, there is considerable confusion, some investigators refusing to admit its existence as a true disease entity. There is ample reason for this. On reading over the published case reports, it soon becomes evident that they deal with a group of diseases and not with a single disease. The group now includes any condition showing leukopenia and neutropenia, no matter what the cause or the clinical picture. The clinical features, including symptomatology, physical observations, pathology and treatment, are abundantly described in the literature, but one must read many publications before all phases of the disease can be fully covered or the information sought obtained. Important textbooks and systems of medicine contain only a brief discussion of the condition. This paper, arranged in more or less textbook fashion, represents a review of the established observations. DEFINITION Neutropenia is a grave disease

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