A Report on Phosphatidylcholine Therapy in a down Syndrome Child

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Abstract
Recent research has given support to the hypothesized existence of impaired cholinergic systems in young Down Syndrome individuals. In this study, a 2 ½-yr.-old Down Syndrome boy was given a phosphatidylcholine supplement over a 7-mo. period. Measures of the EEG indicate a normalization during the treatment period with minor reoccurrence of abnormalities during a placebo period. The child showed a definitive increase in speech and language skills as well as general motor skills which exceeded same aged Down Syndrome peers experiencing like training programs. These data, although preliminary, are part of a larger group study in progress and suggest that phosphatidylcholine therapy may be useful for improving neurophysiological and intellectual functioning of some Down Syndrome children.