Nonconcordance between Clinical Impression and Laboratory Findings in Clinical Toxicology

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Abstract
Davidow and his colleagues [1969] pointed out the high percentage of occurrence of unexpected substances of toxicologic importance in [human] post mortem material. Since that time several studies have confirmed the poor accuracy of clinical diagnoses of toxic disease. Each succeeding study has confirmed Davidow''s assertion that more and/or other drugs will be found than were suspected by the attending physician, or pathologist, on the basis of the clinical information available to them. The purpose of this study was to provide the laboratory confirmation [using 450 cases from Denver, Colorado, USA] of the emergency room or other clinical unit impression of drug distribution in their clinical material.

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