Do Changes in End-Tidal Pco2 Quantitatively Reflect Changes in Cardiac Output?

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Abstract
Ted if timing of the measurements in each episode of hemodynamic perturbation is standardized. In 24 patients undergoing abdominal aortic aneurysm surgery with constant ventilation, we prospectively performed 33 measurements of CO, Petco2, and CO2 elimination (Veco2) within 10 min of hemodynamic changes. The percent decrease in Petco2 directly correlated with the percent decrease in CO (slope = 0.33, r2 = 0.82). Also, the percent decrease in Veco2 correlated with the percent decrease in CO similarly (slope = 0.28, r2 = 0.84). The changes in Petco2 and Veco2 following hemodynamic perturbation were parallel. This finding suggests that decreases in Petco2 quantitatively reflect the decreases in CO2 elimination. A part of this work was presented at the 1992 Annual Meeting of the Americal Society of Anesthesiologists in Washington, DC. Address correspondence and reprint requests to Kinichi Shibutani MD PhD, Department of Anesthesiology, New York Medical College, Valhalla, NY 10595. Accepted for Publication July 6, 1994 © 1994 International Anesthesia Research Society...

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