Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China
- 15 November 2007
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 153 (1) , 211-217
- https://doi.org/10.1007/s00705-007-1083-1
Abstract
A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming from H5N1, H9N2 and other lineages from poultry in Asia. Amino acid motifs within the haemagglutinin sequence of A/Swine/Shandong/nb/2003 suggested it may be able to infect people, whereas the sequences of the other three isolates suggested they would not have had that capability. Our analysis emphasizes the need for a comprehensive study of the interactions between H5N1 and H9N2 viruses in Asia that includes sequencing and phylogenetic investigation.Keywords
This publication has 17 references indexed in Scilit:
- Establishment of multiple sublineages of H5N1 influenza virus in Asia: Implications for pandemic controlProceedings of the National Academy of Sciences, 2006
- Human Infection with an Avian H9N2 Influenza A Virus in Hong Kong in 2003Journal of Clinical Microbiology, 2005
- Phylogenetic Analysis of Eight Genes of H9N2 Subtype Influenza Virus: A Mainland China Strain Possessing Early Isolates’ Genes that have been CirculatingVirus Genes, 2005
- Continuing Evolution of H9N2 Influenza Viruses in Southeastern ChinaJournal of Virology, 2004
- Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern AsiaNature, 2004
- The index influenza A virus subtype H5N1 isolated from a human in 1997 differs in its receptor-binding properties from a virulent avian influenza virusJournal of General Virology, 2004
- H9N2 Influenza A Viruses from Poultry in Asia Have Human Virus-like Receptor SpecificityVirology, 2001
- Characterization of the Pathogenicity of Members of the Newly Established H9N2 Influenza Virus Lineages in AsiaVirology, 2000
- Basic local alignment search toolJournal of Molecular Biology, 1990
- Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acidNature, 1988