The Electrophoretic Analysis of Tetanal Antitoxic Horse-Sera
Open Access
- 1 February 1941
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 40 (2) , 173-177
- https://doi.org/10.4049/jimmunol.40.2.173
Abstract
Summary: Electrophoretic analyses have been made of the sera of several horses hyperimmunized against tetanal toxin. Mobility measurements show that each of these sera contains a large new T-component having u = ca −2.0 × 10−5 cm2 sec−1 volt−1. The serum of one horse was studied at various stages of the hyper-immunizing process; this new T-peak became prominent when a large amount of antitoxin appeared in the serum. In spite of this obvious association of antitoxic activity with T, the areas under the T-peaks cannot be taken as proportional to the measured antitoxic activity.Keywords
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