CELL-CYCLE MANIPULATION OF HUMAN-LEUKEMIC PROGENITOR CELLS WITH HUMORAL ADJUSTMENT INVITRO

  • 1 January 1981
    • journal article
    • research article
    • Vol. 58  (1) , 179-182
Abstract
The cell-cycle change of human leukemic colony-forming cells was studied using a new agar culture method featuring daily feeding of new culture medium with or without leukocyte conditioned medium (LCM). Leukemic cells could be kept out of cycle by withholding LCM from daily feeding and put back into cycle by adding LCM to the daily feeding. [Regulation of leukemic cells between cycling and resting states by humoral adjustments will enable studying of the growth regulation of leukemia and might open up a new avenue for treatment of leukemia.].

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