Definition of DRw10 specificity by restriction fragment length polymorphism
- 1 September 1988
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 32 (3) , 113-120
- https://doi.org/10.1111/j.1399-0039.1988.tb01646.x
Abstract
The purpose of this study was the RFLP characterization of the DRw10 specificity. Twenty‐two DRw10 cells were tested: the DNAs were digested by seven restriction enzymes and hybridized with DRβ, DQβ and DUα probes. Hybridizaton with DRβ revealed a pattern particular to the DRw10 specificity. with a specific Taql 12.5Kb fragment. Hybridization with both DQ‐specific probes showed that DRw10 is always associated with a special DOw1 subtype: DQw5. Furthermore. at DR and DQ levels, the 22 DRw10 cells behaved homogeneously.This publication has 13 references indexed in Scilit:
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