Evolution of two actin genes in the sea urchinStrongylocentrotus franciscanus
- 1 October 1985
- journal article
- research article
- Published by Springer Nature in Journal of Molecular Evolution
- Vol. 22 (2) , 108-116
- https://doi.org/10.1007/bf02101689
Abstract
The complete nucleotide sequences of two chromosomally linked actin genes from the sea urchinStrongylocentrotus franciscanus are presented. The genes are separated by 5.7 kilobases, occur in the same transcriptional orientation, and contain introns in identical positions. The structures and nucleotide sequences of the two genes are extremely similar, suggesting that they arose through a recent duplication. Comparison of the nucleotide sequences of the genes allows inferences to be made about mutational mechanisms active since the duplication event. Whereas point mutations predominate in the coding regions, the introns and flanking DNA are more heavily influenced by a variety of events that cause simultaneous changes in short regions of DNA.Keywords
This publication has 26 references indexed in Scilit:
- The frequency of matching sequences in DNAJournal of Theoretical Biology, 1984
- The phylogeny of the hominoid primates, as indicated by DNA-DNA hybridizationJournal of Molecular Evolution, 1984
- Structural intermediates of deletion mutagenesis: a role for palindromic DNA.Proceedings of the National Academy of Sciences, 1984
- Regulation of Nonmuscle Actin Gene Expression during Early DevelopmentPublished by Elsevier ,1984
- Two Drosophila actin genes in detail gene structure, protein structure and transcription during developmentJournal of Molecular Biology, 1983
- Model for the participation of quasi-palindromic DNA sequences in frameshift mutation.Proceedings of the National Academy of Sciences, 1982
- On the formation of spontaneous deletions: The importance of short sequence homologies in the generation of large deletionsCell, 1982
- The actin genes of drosophila: Protein coding regions are highly conserved but intron positions are notCell, 1981
- The evolution of genes: the chicken preproinsulin geneCell, 1980
- Frameshift Mutations and the Genetic CodeCold Spring Harbor Symposia on Quantitative Biology, 1966