Loss of membrane B2 microglobulin in eccrine porocarcinoma. Its association with the histopathologic and clinical criteria of malignancy

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Abstract
A sensitive immunoperoxidase method employs a new chicken anti-B2-microglobulin (B2M) antibody for use on paraffin sections. The method demonstrates the loss of B2M from the cell membranes of patients with malignant eccrine poromas. This is correlated with the histopathologic and clinical criteria of malignancy.