SEROLOGIC RESPONSE IN BLASTOMYCOSIS - DIAGNOSTIC-VALUE OF DOUBLE IMMUNODIFFUSION ASSAY
- 1 January 1981
- journal article
- research article
- Published by Elsevier
- Vol. 123 (2) , 209-212
- https://doi.org/10.1164/arrd.1981.123.2.209
Abstract
Double immunodiffusion (DID) is a useful, inexpensive antibody screening test that is more specific than complement fixation for blastomycosis. Seven of 10 patients with proved blastomycosis had positive results on DID assays for antibody to the A antigen of Blastomyces dermatitidis. Sputum cytologic examination and skin or other tissue biopsies may be diagnostic. If the organism is demonstrated. Culture remains indispensable for diagnosis and a negative DID test result for A precipitin does not rule out this infection. Follow-up serologic studies of patients in remission and in relapse should be undertaken to determine the evolution of the immune response to the A antigen.This publication has 9 references indexed in Scilit:
- Preparation of reference antisera for laboratory diagnosis of blastomycosisJournal of Clinical Microbiology, 1979
- Acute Pulmonary Blastomycosis in Children: Clinical Course and Follow-upPediatrics, 1979
- Acute Miliary Blastomycosis Presenting as Fulminating Respiratory FailureChest, 1979
- SELF-LIMITED BLASTOMYCOSIS - REPORT OF 13 CASESPublished by Elsevier ,1979
- An unusual case of North American blastomycosisArchives of Dermatology, 1978
- Endogenous Activation in BlastomycosisAnnals of Internal Medicine, 1978
- MICONAZOLE TREATMENT OF RELAPSED PULMONARY BLASTOMYCOSISPublished by Elsevier ,1978
- Exfoliative Cytology in the Rapid Diagnosis of Pulmonary BlastomycosisChest, 1977
- DISSEMINATED PULMONARY BLASTOMYCOSIS IN AN IMMUNOSUPPRESSED PATIENT - DIAGNOSIS BY FIBEROPTIC BRONCHOSCOPYPublished by Elsevier ,1976