Synthesis of selective SRPK-1 inhibitors: Novel tricyclic quinoxaline derivatives
- 1 July 2005
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (13) , 3241-3246
- https://doi.org/10.1016/j.bmcl.2005.04.064
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Novel CCR1 antagonists with improved metabolic stabilityBioorganic & Medicinal Chemistry Letters, 2004
- Comparison of Predictive Ability of Water Solubility QSPR Models Generated by MLR, PLS and ANN MethodsMini-Reviews in Medicinal Chemistry, 2004
- Quinoxalin-2-onesIl Farmaco, 2003
- Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 1: SAR Exploration and Effective Bioisosteric Replacement of a phenyl substituentBioorganic & Medicinal Chemistry Letters, 2003
- Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitorBioorganic & Medicinal Chemistry Letters, 2003
- Reliability of logP Predictions Based on Calculated Molecular Descriptors: A Critical ReviewCurrent Medicinal Chemistry, 2002
- Identification of SRPK1 and SRPK2 as the Major Cellular Protein Kinases Phosphorylating Hepatitis B Virus Core ProteinJournal of Virology, 2002
- Design, Synthesis, and Biological Evaluation of Analogues of the Antitumor Agent, 2-{4-[(7-Chloro-2-quinoxalinyl)oxy]phenoxy}propionic Acid (XK469)Journal of Medicinal Chemistry, 2001
- Chromatographic Hydrophobicity Index by Fast-Gradient RP-HPLC: A High-Throughput Alternative to log P/log DAnalytical Chemistry, 1997
- Tyrphostins. 5. Potent Inhibitors of Platelet-Derived Growth Factor Receptor Tyrosine Kinase: Structure−Activity Relationships in Quinoxalines, Quinolines, and Indole TyrphostinsJournal of Medicinal Chemistry, 1996