Red Cells for Transfusion

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Abstract
The current innovation in the preservation of red cells for transfusion is adenine. Adenine in the storage medium increases ATP content and enhances red-cell viability. A formula called citrate phosphate dextrose adenine (CPDA-1) has a bright new FDA license permitting its use for the storage of whole blood or red cells for as long as 35 days.1 During World War II, the red cells left after the plasma from citrated blood was harvested were stored in corn syrup before use. The anticoagulant was modified later to provide pure dextrose and to lower the pH, and acid citrate dextrose (ACD) solutions . . .